In several design science research (DSR) frameworks and methods, the need for generalising problemsand solutions has been emphasised. For example, various DSR studies present generalised designprinciples as nascent theories. Due to the creative and contextual nature of DSR, several scholars reportthat generalisation can be challenging. The challenge is particularly valid for single qualitative studiesbecause the design of an artefact always reflects the circumstances in the context where it is to be used.Therefore, the purpose of this study is to present guidelines regarding generalisation. The suggestedguidelines are: strategically plan the generalisation process, validate the generalised knowledge toaugment the reusability and find an appropriate generalisation level. The formulation of the guidelinesis based on the analyses of three DSR projects and insights from previous knowledge. Our knowledgecontribution consists of prescriptive knowledge (guidelines) as a complement to existing explanativeand descriptive knowledge.