There are several methods for measuring websites’ usability and accessibility. Some involve users while others do not. This study explores the differences between these types of methods. Their strengths and weaknesses, and if the methods influence the results have been most important. This study also wants to add to the lacking amount of research regarding these two types of methods in relation to the Nielsen’s heuristics. Two methods have been used to analyze two websites, such as usability testing with twelve different people and a website analysis. Nielsen’s heuristics have been used as the theoretical framework for this study. This model attempts to understand how usability works in practice. The model is used to understand the different methods’ differences. The results indicated that methods involving users were more time consuming compared to methods that do not. Methods involving users, however, were more effective in identifying usability and accessibility related problems. Methods involving users can therefore be seen as a more thorough evaluation while methods involving users can be seen as more general. The study identified Nielsen’s heuristics as a promising tool to analyze methods, for example to make sure that the chosen methods complement each other, rather than hinder each other. This study is limited by the number of methods used. Therefore, further research could focus on other types of methods.