The innovative advancements of information communication technology (ICT) combined with a globalized economy have given rise to organizational forms that manipulate time and distance. Today, competitive advantages are more elusive than tangible as a result of dynamically complex environments motivating organizations to adjust in structure and functional capacity. New emergent forms of organizational structures have resulted in the virtual organization (VO), which employs a network structure and allows organizations the flexibility to perform core processes amongst distributed teams, units, departments, and/or organizations. In essence the virtual organization may be viewed as a strategic response to dynamic environmental forces that have encouraged organizations to rethink the concept of competitiveness. Virtual organizations have gained popularity throughout the last decade as a more effective way of managing and communicating information within and across organizations. Information communication technology (ICT) has aided in the globalizing effect of informationalism. The informational flows within a virtual organization have direct bearing on individual and group efforts to obtain and employ information essential to organizational objectives. This thesis investigates the information interchange within virtual organizations through a theoretical study, which converges identified relevant subject areas and introduces the Media Rich Social Information Interchange (MERiSii) model. The empirical study is designed to further investigate the validity of theoretical concepts employed in the MERiSii model and to expand its development to facilitate the function of information interchange. VGR-IT is an IT infrastructure provider, for hospitals and healthcare facilities in the Västra Götaland region of Sweden. Interviews conducted with an account manager for VGR-IT and an IT strategist for Borås Hospital give insight into the communicative tasks of information interchange that must be effective to support the core processes within VGR-IT and the service VGR-IT provides to Borås hospital. The results of a comparative analysis between the theoretical and empirical studies support a revised MERiSii model that may be implicated in future research to further verify its effectiveness.