This chapter examines distributed agency and materiality in practices by proposing posthumanism as a frame for practice-based information studies. Drawing on a posthumanist body of work in social theory, the authors reflect on the information-related activities carried out among geographically dispersed citizen scientists in relation to species abundances and the applications and information systems they use when conducting voluntary monitoring of the Swedish flora and fauna. Central to the chapter are notions concerning the inseparability between the organic and the material in terms of how seeking, sharing, organising, documenting, and other means of interaction with information are conducted in relation to other species and material objects. The significance of material arrangements and the interweaving of agency among numerous species are thus accentuated through rich descriptions of theoretical as well as empirical illustrative examples. The chapter ends with a summary of the theoretical focus of enquiry, including suggestions for possible directions for future research adopting posthuman and multispecies perspectives to studies of information practices.