This study investigates teachers in the Swedish ten-year compulsory school who use ICT (Information and communication technology) in their classroom practice. It poses and gives answers to questions about what is contributing most to explain why they choose to use computers and information technology in their work with students/pupils and uses multiple regression analysis in order to investigate the best pattern of predictive variables. A significant model emerged suggesting that teachers using ICT with students were interested in changing their classroom practice. They also felt self-efficacious in using computers in education and they have positive attitudes toward using ICT in education. The present investigation differs from other studies in that it examines teachers who already are using technology in their classroom practice and it could be seen as a building block in the development of knowledge about how teachers can become more competent and confident in using ICT in their pedagogical work in classroom practice.