The purpose of this study was to investigate the influence of aging on the properties of high-density polyethylene (HDPE) reinforced with multi-wall carbon nanotubes (MWCNTs). Nanocomposites were prepared with nanotubes at 0, 1, 3, and 5 wt%. The long-term durability of the prepared materials was evaluated by thermo-oxidative aging test. Test bodies were aged at 110°C for up to 10 weeks. The nanocomposites were characterized by differential scanning calometry, thermogravimetric analysis (TGA), 13C-NMR, elongation at break, and transmission electron microscopy. The aging mainly occurred on the surface of the samples and the neat HDPE showed a strong yellowing after the aging. A strong reduction in elongation at break was seen. For neat HDPE, the elongation at break was reduced from roughly 1400–25%. When HDPE was reinforced with the nanotubes, the reduction was less dramatic