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  • 51. Márquez, Juan Carlos
    et al.
    Ferreira, Javier
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Seoane, Fernando
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Textile Electrode Straps for Wrist-to-Ankle Bioimpedance Measurements for Body Composition Analysis. Initial Validation & Experimental Results2010Ingår i: Proceedings of the 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society"Merging Medical Humanism and Technology", 2010Konferensbidrag (Refereegranskat)
    Abstract [en]

    Electrical Bioimpedance (EBI) is one of the non-invasive monitoring technologies that could benefit from the emerging textile based measurement systems. If reliable and reproducible EBI measurements could be done with textile electrodes, that would facilitate the utilization of EBI-based personalized healthcare monitoring applications. In this work the performance of a custom-made dry-textile electrode prototype is tested. Four-electrodes ankle-to-wrist EBI measurements have been taken on healthy subjects with the Impedimed spectrometer SFB7 in the frequency range 5 kHz to 1 MHz. The EBI spectroscopy measurements taken with dry electrodes were analyzed via the Cole and Body Composition Analysis (BCA) parameters, which were compared with EBI measurements obtained with standard electrolytic electrodes. The analysis of the obtained results indicate that even when dry textile electrodes may be used for EBI spectroscopy measurements, the measurements present remarkable differences that influence in the Cole parameter estimation process and in the final production of the BCA parameters. These initial results indicate that more research work must be done to in order to obtain a textile-based electrode that ensures reliable and reproducible EBI spectroscopy measurements.

  • 52.
    Márquez, Juan Carlos
    et al.
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Seoane, Fernando
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Lindecrantz, Kaj
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Textrode functional straps for bioimpedance measurements-experimental results for body composition analysis2013Ingår i: European Journal of Clinical Nutrition, ISSN 0954-3007, E-ISSN 1476-5640, Vol. 67, nr Suppl 1, s. 22-27Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background/Objectives:Functional garments for physiological sensing purposes have been used in several disciplines, that is, sports, firefighting, military and medicine. In most of the cases, textile electrodes (textrodes) embedded in the garment are used to monitor vital signs and other physiological measurements. Electrical bioimpedance (EBI) is a non-invasive and effective technology that can be used for the detection and supervision of different health conditions.EBI technology could make use of the advantages of garment integration; however, a successful implementation of EBI technology depends on the good performance of textrodes. The main drawback of textrodes is a deficient skin-electrode interface that produces a high degree of sensitivity to signal disturbances. This sensitivity can be reduced with a suitable selection of the electrode material and an intelligent and ergonomic garment design that ensures an effective skin-electrode contact area.Subjects/Methods:In this work, textrode functional straps for total right side EBI measurements for body composition are presented, and its measurement performance is compared against the use of Ag/AgCl electrodes. Shieldex sensor fabric and a tetra-polar electrode configuration using the ImpediMed spectrometer SFB7 in the frequency range of 3-500 kHz were used to obtain and analyse the impedance spectra and Cole and body composition parameters.Results:The results obtained show stable and reliable measurements; the slight differences obtained with the functional garment do not significantly affect the computation of Cole and body composition parameters.Conclusions:The use of a larger sensor area, a high conductive material and an appropriate design can compensate, to some degree, for the charge transfer deficiency of the skin-electrode interface.

  • 53. Pau, I.
    et al.
    Seoane Martínez, Fernando
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Lindecrantz, Kaj
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Valero, M.A.
    Carracedo, J.
    Home e-health system integration in the Smart Home through a common media server2009Konferensbidrag (Övrigt vetenskapligt)
  • 54. Reza Atefi, Seyed
    et al.
    Seoane, Fernando
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Buendia, Ruben
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Lindecrantz, Kaj
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Cole Function and Conductance-Based Parasitic Capacitance Compensation for Cerebral Electrical Bioimpedance Measurements2012Konferensbidrag (Refereegranskat)
    Abstract [en]

    One of the most common measurement artifacts present in Electrical Bioimpedance Spectroscopy measurements (EBIS) comes from the capacitive leakage effect resulting from parasitic stray capacitances. This artifact produces a deviation in the measured impedance spectrum that is most noticeable at higher frequencies. The artifact taints the spectroscopy measurement increasing the difficulty of producing reliable EBIS measurements at high frequencies. In this work, an approach for removing such capacitive influence from the spectral measurement is presented making use of a novel method to estimate the value of the parasitic capacitance equivalent that causes the measurement artifact. The proposed method has been tested and validated theoretically and experimentally and it gives a more accurate estimation of the value of the parasitic capacitance than the previous methods. Once a reliable value of parasitic capacitance has been estimated the capacitive influence can be easily compensated in the EBIS measured data. Thus enabling analysis of EBIS data at higher frequencies, i.e. in the range of 300-500 kHz like measurements intended for cerebral monitoring, where the characteristic frequency is remarkably higher than EBIS measurements i.e. within the range 30 to 50 kHz, intended for body composition assessment.

  • 55. Schneegass, Stefan
    et al.
    Hassib, Mariam
    Zhou, Bo
    Cheng, Jingyuan
    Seoane, Fernando
    Högskolan i Borås, Akademin för vård, arbetsliv och välfärd. KTH-School of Technology and Health.
    Amft, Oliver
    Lukowicz, Paul
    Schmidt, Albrecht
    SimpleSkin: towards multipurpose smart garments2015Ingår i: Proceedings of the 2015 ACM International Joint Conference on Pervasive and Ubiquitous Computing and Proceedings of the 2015 ACM International Symposium on Wearable Computers, ACM Publications, 2015, s. 241-244Konferensbidrag (Refereegranskat)
  • 56.
    Seoane, Fernando
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Current Source for Multifrequency Broadband Electrial Bioimpedance Spectroscopy Systems. A Novel Approach.2006Konferensbidrag (Refereegranskat)
  • 57.
    Seoane, Fernando
    et al.
    Högskolan i Borås, Akademin för vård, arbetsliv och välfärd. KTH-School of Technology and Health.
    Abtahi, Shirin
    Karolinska University Hospital.
    Abtahi, Farhad
    KTH-School of Technology and Health.
    Ellegård, Lars
    Sahlgrenska University Hospital.
    Johannsson, Gudmundur
    Sahlgrenska University Hospital.
    Bosaeus, Ingvar
    University of Gothenburg.
    Ward, Leigh
    University of Queensland.
    Slightly superior performance of bioimpedance spectroscopy over single frequency regression equations for assessment of total body water2015Konferensbidrag (Refereegranskat)
  • 58.
    Seoane, Fernando
    et al.
    Högskolan i Borås, Akademin för vård, arbetsliv och välfärd. KTH-School of Technology and Health.
    Abtahi, Shirin
    Karolinkska University Hospital.
    Abtahi, Farhad
    KTH-School of Technology and Health.
    Ellegård, Lars
    University of Gothenburg.
    Johannsson, Gudmundur
    University of Gothenburg.
    Bosaeus, Ingvar
    University of Gothenburg.
    Ward, Leigh C
    University of Queensland.
    Mean Expected Error in Prediction of Total Body Water.: A True Accuracy Comparison between Bioimpedance Spectroscopy and Single Frequency Regression Equations.2015Ingår i: BioMed Research International, ISSN 2314-6133, E-ISSN 2314-6141, Vol. 2015Artikel i tidskrift (Refereegranskat)
  • 59.
    Seoane, Fernando
    et al.
    Högskolan i Borås, Akademin för textil, teknik och ekonomi. Högskolan i Borås, Akademin för vård, arbetsliv och välfärd. Karolinska Institutet.
    Atefi, Seyed Reza
    Högskolan i Borås, Akademin för textil, teknik och ekonomi. Harvard Univsersity.
    Electrical bioimpedance enabling prompt intervention in traumatic brain injury2017Ingår i: SPIE Micro-and Nanotechnology Sensors, Systems, and Applications IX, 2017Konferensbidrag (Refereegranskat)
  • 60.
    Seoane, Fernando
    et al.
    Högskolan i Borås, Akademin för vård, arbetsliv och välfärd. KTH-School of Technology and Health.
    Atefi, Seyed Reza
    Harvard Univsersity.
    Tomner, Jens
    Karolinska Hospital.
    Kostulas, Konstantinos
    Karolinska Hospital.
    Lindecrantz, Kaj
    KTH-School of Technology and Health.
    Electrical Bioimpedance Spectroscopy on Acute Unilateral Stroke Patients: Initial Observations regarding Differences between Sides2015Ingår i: BioMed research international, Vol. 2015Artikel i tidskrift (Refereegranskat)
  • 61.
    Seoane, Fernando
    et al.
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Bragós, Ramon
    Lindecrantz, Kaj
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Current Source for Wideband Multifrequency Electrical Bioimpedance Measurements2006Ingår i: IEEE Transactions on Biomedical Circuits and Systems, ISSN 1932-4545, E-ISSN 1940-9990, s. 5121-5125Artikel i tidskrift (Övrigt vetenskapligt)
  • 62.
    Seoane, Fernando
    et al.
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Bragós, Ramon
    Lindecrantz, Kaj
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Riu, Pere J.
    Current Source Design for Electrical Bioimpedance Spectroscopy2008Ingår i: Encyclopaedia of Healthcare Information Systems, Encyclopaedia of Healthcare Information Systems , 2008Kapitel i bok, del av antologi (Övrigt vetenskapligt)
  • 63.
    Seoane, Fernando
    et al.
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Bragós, Ramón
    Lindecrantz, Kaj
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Current Source for Wideband Electrical Bioimpedance Spectroscopy Based on a Single Operational Amplifier.2006Konferensbidrag (Refereegranskat)
    Abstract [en]

    Traditionally, measurements of electrical bioimpedance for medical diagnostic purposes have used only low frequencies, usually below 100 kHz. The analysis focused only on the resistive part of the impedance; very often at low frequencies the reactive part of the impedance is negligible. Recent studies of the electrical bioimpedance spectrum, both real and imaginary parts, have indicated new potential applications e.g. detection of meningitis, skin cancer assessment and brain cellular edema detection. An important functional unit in a wideband impedance spectrometer is the current source used to inject the current into the tissue under study. A current source must provide an output current virtually constant over the frequency range of interest and independent of the load at the output. Several designs have been proposed over the years but the performance of them all degraded markedly near bellow 1 MHz e.g. Ackmann in 1993, Bragos et al in 1994 and Bertemes-Filho et al in 2000. The development of electronic technology has made available devices that allow us to obtain a current source with large output impedance, larger than 100 k Omega, above I MHz and based in a simple single Op-Amp circuit topology. Simulation results and experimental measurements are compared and the most important parameters of the VCCS are analytically studied and experimentally tested, including the dependency to changes in the circuit elements and the incidence of the Op-Amp parameters on the current source features.

  • 64.
    Seoane, Fernando
    et al.
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Ferreira, Javier
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Buendia, Ruben
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Lindecrantz, Kaj
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Adaptive Frequency Distribution for Electrical Bioimpedance Spectroscopy Measurements2012Konferensbidrag (Refereegranskat)
    Abstract [en]

    This paper presents a novel frequency distribution scheme intended to provide more accurate estimations of Cole parameters. Nowadays a logarithmic frequency distribution is mostly used in Electrical Bioimpedance Spectroscopy (EBIS) applications. However it is not optimized following any criterion. Our hypothesis is that an EBIS signal contains more information where the variation of the measurement regarding the frequency is larger; and that there ought to be more measuring frequencies where there is more information. Results show that for EBIS data with characteristic frequencies up to 200 kHz the error obtained with both frequency distribution schemes is similar. However, for EBIS data with higher values of characteristic frequency the error produced when estimating the values from EBIS measurements using an adaptive frequency distribution is smaller. Thus it may usefull for EBIS applications with high values of characteristic frequency, e.g. cerebral bioimpedance.

  • 65.
    Seoane, Fernando
    et al.
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Ferreira, Javier
    José Sanchéz, Juan
    Bragós, Ramon
    An Analog Front-End Enables Electrical Impedance Spectroscopy System On-Chip for Biomedical Applications2008Ingår i: Physiological Measurement, ISSN 0967-3334, E-ISSN 1361-6579, Vol. 29, nr 6Artikel i tidskrift (Övrigt vetenskapligt)
    Abstract [en]

    The increasing number of applications of electrical bioimpedance measurement in biomedical application together with the continuous advances in the textile technology applied in the design and development of biopotential electrodes has encouraged several researchers to do the first attempts to develop portable electrical bioimpedance measurement systems and even wearable. The main aim of these systems is mainly home-monitoring. Analog Devices has provided us with the AD5933, a new system-on-chip fully integrated electrical impedance spectrometer which might allow the implementation of minimal size instrumentation for electrical bioimpedance measurements. This system, however, performs a 2-Electrode measurement and thus is not suitable for most of the spectroscopy applications of electrical bioimpedance. In this work we present a relatively simple analog front-end that adapts the AD5933 to a 4-Electrode strategy, allowing its use in biomedical applications. The resulting impedance measurements exhibit a better performance in aspects like load dynamic range and accuracy. These type of minimum-size, AD5933-based bioimpedance measurement systems would lead the researcher to develop and implement light and wearable electrical bioimpedance systems for monitoring applications, a new a huge niche for medical technology development

  • 66.
    Seoane, Fernando
    et al.
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Ferreira, Javier
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Marquez, Juan Carlos
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Skrifvars, Mikael
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Conductive Polymer Films as Textrodes for Biopotential Sensing2011Konferensbidrag (Övrigt vetenskapligt)
    Abstract [en]

    Introduction: After several years of progresses in textile technology and wearable measurement instrumentation, applications of wearable textile-electronics systems are arising providing a stable background for commercial applications. So far, the available commercial solutions are centered on fitness applications and mostly based in the acquisition of heart rate through Textile Electrodes (Textrodes) based on metallic threads or on conductive rubber compounds. Methods and Materials: In this work a novel material approach is presented to produce Textrodes for acquisition of Electrocardiographic (ECG) signals using a conductive polypropylene (PP1386 from Premix, Finland) polymer material. The polymer was film extruded into thin films, and used as such in the Textrode. Conductive Polymer Films (CPF) have been used to produce Textrodes, and its measurement performance has been compared with the ECG signals obtained with commercial Textrode fabrics and conventional Ag/AgCl electrodes. In order to set up the same measurement conditions, a chest strap tailored to host the testing electrodes has been used. Results: The close resemblance of the ECG acquired with the textile fabric electrodes, the Ag/AgCl electrodes and the PP1386 CPF electrodes suggest that the Polymer Electrodes PP1386 are a feasible alternative to the current textile fabrics that use silver thread as conductive material and also to conductive rubber material. Discussion & Conclusion: The availability of the Conductive Polymer Electrode PP1386 in a film form allows the manufacturing of electrodes by conventional textile processes, like lamination or sewing, therefore facilitating the transition from lab prototyping to industrial manufacturing. Replacing the traditional silver thread as conductive element in the fabrication of Textrodes will definitely reduce the material cost per Textrode. Biocompatibility issues and manufacturability issues must be addressed but the exhibited functional performance is showing encouraging results.

  • 67.
    Seoane, Fernando
    et al.
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Garrote Jurado, Ramon
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Christie, Michael
    Design-Build Experience-Based Program in Biomedical Engineering as a Practical Example of Science for Professions2010Ingår i: Proceedings of EDULEARN10: International Conference on Education and New Learning Technologies, International Association of Technology, Education and Development , 2010, s. 110-113Konferensbidrag (Refereegranskat)
    Abstract [en]

    Aiming to implement the Motto “Science for Professions” follow at the University of Borås, the school of engineering has carry out a series of Design-Building Experiences (DBE) aimed to promote the development of specific engineering skills and attributes as well as personal and interpersonal competences on team work and communications, which have been selected from the CDIO syllabus. A total of three DBE activities have been implemented in a one-year master program in Biomedical Engineering. The learning outcome produce from the implementation of the teaching-learning activity has been evaluated from the point of view of the students, through a questionnaire. The answers from the students suggest that the activity has reached the intended goal, especially facilitating the development the students’ own personal and professional engineering skills and attributes. The results of this survey also indicate the remarked concern of the students regarding the assessment of the activity and its contribution in the final grade of the course. In general the implementation of the DBE was a success and provides us with certain new knowledge about implementing student centered learning methods on international master programs.

  • 68.
    Seoane, Fernando
    et al.
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Gawel, J
    Ferreira, J.
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Wirstrand, J.
    Stretchable Circuit Board Technology enabling Seamless Textile-Electronic Integration for Electrical Muscle Stimulation Therapy2012Konferensbidrag (Refereegranskat)
  • 69.
    Seoane, Fernando
    et al.
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Lindecrantz, Kaj
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    A Novel Approach for Estimation of Electrical Bioimpedance: Total Least Square.2007Konferensbidrag (Övrigt vetenskapligt)
  • 70.
    Seoane, Fernando
    et al.
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Lindecrantz, Kaj
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Electrial Bioimpedance Cerebral Monitoring2008Ingår i: Encyclopaedia of Healthcare Information Systems, Encyclopaedia of Healthcare Information Systems. , 2008Kapitel i bok, del av antologi (Övrigt vetenskapligt)
  • 71.
    Seoane, Fernando
    et al.
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Lindecrantz, Kaj
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Enhancement of a voltage controlled current source for wideband electrical bioimpedance spectroscopy2006Konferensbidrag (Övrigt vetenskapligt)
  • 72.
    Seoane, Fernando
    et al.
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Lindecrantz, Kaj
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Extraction of structural information from impedance spectrum data. A step towards the identification of cellular oedema2006Konferensbidrag (Övrigt vetenskapligt)
  • 73.
    Seoane, Fernando
    et al.
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Lindecrantz, Kaj
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Olsson, Torsten
    Kjellmer, Ingemar
    Flisberg, Anders
    Bågenholm, Ralph
    Brain electrical impedance at various frequencies: the effect of hypoxia2004Ingår i: Engineering in Medicine and Biology Society, 2004. EMBC 2004. Conference Proceedings. 26th Annual International Conference of the, 2322 - 2325 Vol.3, 2004Konferensbidrag (Refereegranskat)
    Abstract [en]

    Non-invasive multi-frequency measurements of transcephalic impedance, both reactance and resistance, can efficiently detect cell swelling of brain tissue and can be used for early detection of threatening brain damage. We have performed experiments on piglets to monitor transcephalic impedance during hypoxia. The obtained results have confirmed the hypothesis that changes in the size of cells modify the tissue impedance. During tissue inflammation after induced hypoxia, cerebral tissue exhibits changes in both reactance and resistance. Those changes are remarkably high, up to 71% over the baseline, and easy to measure especially at certain frequencies. A better understanding of the electrical behaviour of cerebral tissue during cell swelling would lead us to develop effective non-invasive clinical tools and methods for early diagnosis of cerebral edema and brain damage prevention.

  • 74.
    Seoane, Fernando
    et al.
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Lindecrantz, Kaj
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Olsson, Torsten
    Kjellmer, Ingemar
    Flisberg, Anders
    Bågenholm, Ralph
    Spectroscopy study of the dynamics of the transencephalic electrical impedance in the perinatal brain during hypoxia2005Ingår i: Physiological Measurement, ISSN 0967-3334, E-ISSN 1361-6579, Vol. 26, nr 5, s. 849-863Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Hypoxia/ischaemia is the most common cause of brain damage in neonates. Thousands of newborn children suffer from perinatal asphyxia every year. The cells go through a response mechanism during hypoxia/ischaemia, to maintain the cellular viability and, as a response to the hypoxic/ischaemic insult, the composition and the structure of the cellular environment are altered. The alterations in the ionic concentration of the intra- and extracellular and the consequent cytotoxic oedema, cell swelling, modify the electrical properties of the constituted tissue. The changes produced can be easily measured using electrical impedance instrumentation. In this paper, we report the results from an impedance spectroscopy study on the effects of the hypoxia on the perinatal brain. The transencephalic impedance, both resistance and reactance, was measured in newborn piglets using the four-electrode method in the frequency range from 20 kHz to 750 kHz and the experimental results were compared with numerical results from a simulation of a suspension of cells during cell swelling. The experimental results make clear the frequency dependence of the bioelectrical impedance, confirm that the variation of resistance is more sensitive at low than at high frequencies and show that the reactance changes substantially during hypoxia. The resemblance between the experimental and numerical results proves the validity of modelling tissue as a suspension of cells and confirms the importance of the cellular oedema process in the alterations of the electrical properties of biological tissue. The study of the effects of hypoxia/ischaemia in the bioelectrical properties of tissue may lead to the development of useful clinical tools based on the application of bioelectrical impedance technology.

  • 75.
    Seoane, Fernando
    et al.
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Lu, Mai
    Persson, Mikael
    Lindecrantz, Kaj
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Electrical Bioimpedance Cerebral Monitoring. A Study of the Current Density Distribution and Impedance Sensitivity Maps on a 3D Realistic Head Model2007Ingår i: Proceedings of the 3rd International IEEE EMBS Conference on Neural Engineering, IEEE , 2007Konferensbidrag (Refereegranskat)
    Abstract [en]

    There have been several studies of the application of electrical bioimpedance technology for brain monitoring in the past years. They have targeted a variety of events and injuries e.g. epilepsy or stroke. The current density distribution and the voltage lead field associated with an impedance measurement setup is of critical importance for the proper analysis of any dynamics in the impedance measurement or for an accurate reconstruction of an EIT image, specially a dynamic type. In this work for the first time, the current density distribution is calculated in a human head with anatomical accuracy and resolution down to 1 mm, containing up to 24 tissues and considering the frequency dependency of the conductivity of each tissue. The obtained current densities and the subsequent sensitivity maps are analyzed with a special focus on the dependency of the electrode arrangement and also the measurement frequency. The obtained results provide us with interesting and relevant information to consider in the design of any tool for electrical bioimpedance cerebral monitoring.

  • 76.
    Seoane, Fernando
    et al.
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Lu, Mai
    Persson, Mikael
    Lindecrantz, Kaj
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    The Role of the Cerebrospinal Fluid in the Distribution of Electrical Current within the Brain and its Implications for Electrical Bioimpedance Cerebral Monitoring.2007Konferensbidrag (Refereegranskat)
  • 77.
    Seoane, Fernando
    et al.
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Macias, Raul
    Bragos, Ramon
    Lindecrantz, Kaj
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Simple Voltage-Controlled Current Source for Wideband Electrical Bioimpedance Spectroscopy: Circuit Dependences2011Ingår i: Measurement science and technology, ISSN 0957-0233, E-ISSN 1361-6501, Vol. 22, nr 11, s. 115801-Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    In this work, the single Op-Amp with load-in-the-loop topology as a current source is revisited. This circuit topology was already used as a voltage-controlled current source (VCCS) in the 1960s but was left unused when the requirements for higher frequency arose among the applications of electrical bioimpedance (EBI). The aim of the authors is not only limited to show that with the currently available electronic devices it is perfectly viable to use this simple VCCS topology as a working current source for wideband spectroscopy applications of EBI, but also to identify the limitations and the role of each of the circuit components in the most important parameter of a current for wideband applications: the output impedance. The study includes the eventual presence of a stray capacitance and also an original enhancement, driving with current the VCCS. Based on the theoretical analysis and experimental measurements, an accurate model of the output impedance is provided, explaining the role of the main constitutive elements of the circuit in the source's output impedance. Using the topologies presented in this work and the proposed model, any electronic designer can easily implement a simple and efficient current source for wideband EBI spectroscopy applications, e.g. in this study, values above 150 kΩ at 1 MHz have been obtained, which to the knowledge of the authors are the largest values experimentally measured and reported for a current source in EBI at this frequency

  • 78.
    Seoane, Fernando
    et al.
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Mohino-Herranz, Inmaculada
    Ferreira González, Javier
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Alvarez, Lorena
    Buendia, Ruben
    Ayllón, David
    Cosme, Llerena
    Gil-Pita, Roberto
    Wearable Biomedical Measurement Systems for Assessment of Mental Stress of Combatants in Real Time2014Ingår i: Sensors, ISSN 1424-8220, E-ISSN 1424-8220, Vol. 14, nr 4, s. 7120-7141Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The Spanish Ministry of Defense, through its Future Combatant program, has sought to develop technology aids with the aim of extending combatants' operational capabilities. Within this framework the ATREC project funded by the “Coincidente” program aims at analyzing diverse biometrics to assess by real time monitoring the stress levels of combatants. This project combines multidisciplinary disciplines and fields, including wearable instrumentation, textile technology, signal processing, pattern recognition and psychological analysis of the obtained information. In this work the ATREC project is described, including the different execution phases, the wearable biomedical measurement systems, the experimental setup, the biomedical signal analysis and speech processing performed. The preliminary results obtained from the data analysis collected during the first phase of the project are presented, indicating the good classification performance exhibited when using features obtained from electrocardiographic recordings and electrical bioimpedance measurements from the thorax. These results suggest that cardiac and respiration activity offer better biomarkers for assessment of stress than speech, galvanic skin response or skin temperature when recorded with wearable biomedical measurement systems.

  • 79.
    Seoane, Fernando
    et al.
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Rempfler, Markus
    Marquez, Juan Carlos
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Lindecrantz, Kaj
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Textile-enabled Instrumentation for Impedance Cardiographic Signals2011Konferensbidrag (Övrigt vetenskapligt)
    Abstract [en]

    Research efforts in the areas of Electrical Bioimpedance (EBI) and textile materials with conductive properties have contributed to the proliferation of research projects aiming to test the feasibility of implementing Textile-enabled instrumentation for performing EBI measurements. Most of the work done has been focused on the electrical characterization of the Textrodes (textile electrodes) and on spectroscopy applications of EBI like early detection of Cardiogenic Pulmonary Edema. In this work, a garment composed of two belts containing Textrodes made of conductive Velcro, loops-type, has been manufactured. Both, the abdomen and the neck belts, have four Textrodes connected through a conductive fabric Technik Tex P-130+ Shieldex fabric in pairs. This way, a tetrapolar EBI measurement between the neck and the chest is performed, implementing a typical band electrode arrangement [1] approach with the two belts. Using a custom-made device Respimon that measures the electrical cardiac activity with a 1-lead ECG and a tetrapolar EBI measurement at 50kHz of a portion of the body, and the Textrode garment, the ICG and ECG signals have been recorded and compared with the recordings obtained with Ag/AgCl electrodes placed in the same positions. The resemblance of the ICG and ECG signals obtained with both the Ag/AgCl electrodes and the Textrode garment confirms the feasibility of using Textrodes to perform measurements of cardiac impedance. There are several useful hemodynamic parameters that can be extracted from the ICG signal in combination with the ECG signal. The availability of a Textrode garment, easy to wear and that produces reliable ICG measurements, would contribute to present ICG monitoring as feasible technology for implementing personalized healthcare monitoring systems, especially for e-health applications of heart failure patients management.

  • 80.
    Seoane, Fernando
    et al.
    Högskolan i Borås, Akademin för textil, teknik och ekonomi.
    Soroudi, Azadeh
    Högskolan i Borås, Akademin för textil, teknik och ekonomi.
    Abtahi, Farhad
    KTH, Medicinsk teknik.
    Lu, Ke
    KTH-School of Technology and Health.
    Skrifvars, Mikael
    Högskolan i Borås, Akademin för textil, teknik och ekonomi.
    Printed Electronics Enabling a Textile-friendly Interconnection between Wearable Measurement Instrumentation & Sensorized Garments2016Konferensbidrag (Refereegranskat)
  • 81.
    Seoane, Fernando
    et al.
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Valero, M.A.
    García-Perez, A.
    Gallar, P.
    Implementation of an Open Telenephrology Platform to Support Home Monitoring2008Konferensbidrag (Refereegranskat)
  • 82.
    Seoane, Fernando
    et al.
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Ward, L. C.
    Lindecrantz, Kaj
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Lingwood, B. E.
    Automated criterion-based analysis for Cole parameters assessment from cerebral neonatal electrical bioimpedance spectroscopy measurements2012Ingår i: Physiological Measurement, ISSN 0967-3334, E-ISSN 1361-6579, Vol. 33, nr 8, s. 1363-1377Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Hypothermia has been proven as an effective rescue therapy for infants with moderate or severe neonatal hypoxic ischemic encephalopathy. Hypoxia-ischemia alters the electrical impedance characteristics of the brain in neonates; therefore, spectroscopic analysis of the cerebral bioimpedance of the neonate may be useful for the detection of candidate neonates eligible for hypothermia treatment. Currently, in addition to the lack of reference bioimpedance data obtained from healthy neonates, there is no standardized approach established for bioimpedance spectroscopy data analysis. In this work, cerebral bioimpedance measurements (12 h postpartum) in a cross-section of 84 term and near-term healthy neonates were performed at the bedside in the post-natal ward. To characterize the impedance spectra, Cole parameters (R(0), R(∞), f(C) and α) were extracted from the obtained measurements using an analysis process based on a best measurement and highest likelihood selection process. The results obtained in this study complement previously reported work and provide a standardized criterion-based method for data analysis. The availability of electrical bioimpedance spectroscopy reference data and the automatic criterion-based analysis method might support the development of a non-invasive method for prompt selection of neonates eligible for cerebral hypothermic rescue therapy.

  • 83.
    Seoane Martinez, Fernando
    et al.
    Högskolan i Borås, Akademin för textil, teknik och ekonomi.
    Lindecrantz, Kaj
    Högskolan i Borås, Akademin för textil, teknik och ekonomi.
    Method and apparatus for brain damage detection2011Patent (Övrig (populärvetenskap, debatt, mm))
    Abstract [en]

    The present invention comprises method and apparatus for detecting injury resulting in pathological processes affecting tissue within a portion of the body in a mammal, particularly a human brain. Said method comprises the steps of applying a first and a second pair of electrodes around the periphery of the portion, generating an alternating current at a known current level and applying said current between the first pair of electrodes, detecting and measuring the alternating voltage developed between the second pair of electrodes, and calculating the impedance of said portion. Further, the alternating current is applied between the first pair of electrodes in a series of increasing frequencies ranging within a known spectrum, and the resistance and the reactance for each frequency are detected and plotted against said frequency. The electrical impedance of said portion is calculated for each frequency and plotted into an impedance plot. Said resistance-reactance-and impedance-plots are finally analyzed, and any notable changes compared to normal spectrum profiles and plots are detected and evaluated.

  • 84.
    Seoane Martínez, Fernando
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Electrical bioimpedance cerebral monitoring2007Doktorsavhandling, monografi (Övrigt vetenskapligt)
    Abstract [en]

    Neurologically related injuries cause a similar number of deaths as cancer, and brain damage is the second commonest cause of death in the world and probably the leading cause of permanent disability. The devastating effects of most cases of brain damage could be avoided if it were detected and medical treatment initiated in time. The passive electrical properties of biological tissue have been investigated for almost a century and electrical bioimpedance studies in neurology have been performed for more than 50 years. Even considering the extensive efforts dedicated to investigating potential applications of electrical bioimpedance for brain monitoring, especially in the last 20 years, and the specifically acute need for such non-invasive and efficient diagnosis support tools, Electrical Bioimpedance technology has not made the expected breakthrough into clinical application yet. In order to reach this stage in the age of evidence-based medicine, the first essential step is to demonstrate the biophysical basis of the method under study. The present research work confirms that the cell swelling accompanying the hypoxic/ischemic injury mechanism modifies the electrical properties of brain tissue, and shows that by measuring the complex electrical bioimpedance it is possible to detect the changes resulting from brain damage. For the development of a successful monitoring method, after the vital biophysical validation it is critical to have available the proper electrical bioimpedance technology and to implement an efficient protocol of use. Electronic instrumentation is needed for broadband spectroscopy measurements of complex electrical bioimpedance; the selection of the electrode setup is crucial to obtain clinically relevant measurements, and the proper biosignal analysis and processing is the core of the diagnosis support system. This work has focused on all these aspects since they are fundamental for providing the solid medico-technological background necessary to enable the clinical usage of Electrical Bioimpedance for cerebral monitoring.

  • 85.
    Seoane Martínez, Fernando
    et al.
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Buendia, Ruben
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Gil-Pita, R.
    Cole Parameter Estimation from Electrical Bioconductance Spectroscopy Measurements2010Konferensbidrag (Refereegranskat)
    Abstract [en]

    Several applications of Electrical Bioimpedance (EBI) make use of Cole parameters as base of their analysis, therefore Cole parameters estimation has become a very common practice within Multifrequency- and EBI spectroscopy. EBI measurements are very often contaminated with the influence of parasitic capacitances, which contributes to cause a hook-alike measurement artifact at high frequencies in the EBI obtained data. Such measurement artifacts might cause wrong estimations of the Cole parameters, contaminating the whole analysis process and leading to wrong conclusions. In this work, a new approach to estimate the Cole parameters from the real part of the admittance, i.e. the conductance, is presented and its performance is compared with the results produced with the traditional fitting of complex impedance to a depressed semi-circle. The obtained results prove that is feasible to obtain the full Cole equation from only the conductance data and also that the estimation process is safe from the influence capacitive leakage.

  • 86.
    Seoane Martínez, Fernando
    et al.
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Marquez, J. C.
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Ferreira, Javier
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Buendia, Ruben
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Lindecrantz, Kaj
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    The Challenge of the Skin-Electrode Contact in Textile-enabled Electrical Bioimpedance Measurements for Personalized Healthcare Monitoring Applications2011Ingår i: Biomedical Engineering, Trends in Materials Science / [ed] AN Laskovski, InTech , 2011Kapitel i bok, del av antologi (Övrigt vetenskapligt)
    Abstract [en]

    Textile technology has gone through a remarkable development in the field of Smart Textiles and more specifically in the area of conductive fabrics and yarns. Important research efforts have been done worldwide and especially in Europe, where the EUcommission has supported several research projects in the near past e.g. BIOTEX IST-2004- 016789, CONTEXT IST- 2004-027291 and MyHeart IST-2002-507816. As a result of such worldwide R&D efforts, textile sensors and electrodes are currently available commercially. Nowadays there are even consumer products with textile sensing technology for heart rate monitoring integrated in the apparel e.g. Adistar Fusion T-shirt from Adidas or the Numetrex’s Cardio shirt. Since one of the main areas of focus where R&D efforts have been concentrated is Personalized Healthcare Monitoring (PHM) and the fact that most of the efforts developing textile sensors have been focused on developing electrodes for biopotential signals recording, it is natural that the main targeted application has been the acquisition of electrical biopotentials and especially monitoring the ElectroCardioGraphic activity, but also other types of textile sensors have been investigated e.g. textile stretching sensor (Mattmann et al., 2008). Nowadays textile-enable stretch sensors are available commercially like the one manufactured by Merlin Systems. While the application of this type of sensor aims at other applications than biopotential recordings, an important area of application of stretch sensors still is PHM and fitness. This type of sensors can be used for respiration monitoring or plethysmography applications.

  • 87.
    Seoane Martínez, Fernando
    et al.
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Marquez, J. C.
    Ferreira, Javier
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Buendia, Ruben
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    Lindecrantz, Kaj
    Högskolan i Borås, Institutionen Ingenjörshögskolan.
    The Challenge of the Skin-Electrode Contact in Textile-enabled Electrical Bioimpedance Measurements for Personalized Healthcare Monitoting Application2010Konferensbidrag (Refereegranskat)
  • 88. Vega-Barbas, Mario
    et al.
    Pau, Ivan
    Seoane, Fernando
    Högskolan i Borås, Institutionen för Vårdvetenskap.
    Confidence: dependencies and their critical role in fostering user acceptance in pervasive applications2014Konferensbidrag (Refereegranskat)
    Abstract [en]

    Pervasive computing offers new scenarios where users are surrounded by invisible and proactive technology making smart spaces. Although the utility and power of solutions developed using this computer paradigm are proved, there are unresolved problems that hinder their acceptance and inclusion in our private life. Users have problems understanding the operations of a pervasive computing solution, and therefore they should trust that the solution works properly and according to their expectations. Nevertheless, the concept of trust is already framed in a specific use within the ecosystem of applications that can populate a smart space. To take this concept of trust to the whole space, we propose to study and define the concept of confidence. In contrast to the concept of trust, confidence has deeper psychological implications.

  • 89. Vega-Barbas, Mario
    et al.
    Pau, Ivan
    Valero, Miguel Angel
    Seoane, Fernando
    Högskolan i Borås, Institutionen för Vårdvetenskap.
    Adaptive Software Architecture for Confident Homecare in the Digital Home2014Konferensbidrag (Refereegranskat)
  • 90.
    Vega-Barbas, Mario
    et al.
    Royal Institute of Technology.
    Pau, Iván
    Universidad Politecnica de Madrid.
    Augusto, Juan C
    Middlesex University.
    Seoane, Fernando
    Högskolan i Borås, Akademin för textil, teknik och ekonomi. Högskolan i Borås, Akademin för vård, arbetsliv och välfärd. Karolinska Institutet.
    Interaction patterns for smart spaces. A confident interaction design solution for pervasive sensitive IoT services2017Ingår i: IEEE Access, E-ISSN 2169-3536Artikel i tidskrift (Refereegranskat)
  • 91.
    Vega-Barbas, Mario
    et al.
    KTH-School of Technology and Health.
    Pau, Iván
    Universidad Politecnica de Madrid.
    Ferreira, Javier
    Högskolan i Borås, Akademin för vård, arbetsliv och välfärd. KTH-School of Technology and Health.
    Lebis, Evelyn
    Seoane, Fernando
    Högskolan i Borås, Akademin för vård, arbetsliv och välfärd. KTH-School of Technology and Health.
    Utilizing Smart Textiles-Enabled Sensorized Toy and Playful Interactions for Assessment of Psychomotor Development on Children2015Ingår i: Journal of Sensors, ISSN 1687-725X, E-ISSN 1687-7268, artikel-id 898047Artikel i tidskrift (Refereegranskat)
  • 92.
    Vega-Barbas, Mario
    et al.
    KTH-School of Technology and Health.
    Pau, Iván
    Universidad Politecnica de Madrid.
    Martín-Ruiz, María Luisa
    Universidad Politecnica de Madrid.
    Seoane, Fernando
    Högskolan i Borås, Akademin för vård, arbetsliv och välfärd. KTH-School of Technology and Health.
    Adaptive Software Architecture Based on Confident HCI for the Deployment of Sensitive Services in Smart Homes2015Ingår i: Sensors, ISSN 1424-8220, E-ISSN 1424-8220, Vol. 15, nr 4, s. 7294-7322Artikel i tidskrift (Refereegranskat)
  • 93.
    Wollmann, Thomas
    et al.
    GECKO Institute, Heilbronn University, Heilbronn, Germany.
    Abtahi, Farhad
    KTH-School of Technology and Health.
    Eghdam, Abouzar
    Department of Learning, Informatics, Management and Ethics, Health Informatics Centre, Karolinska Institute.
    Seoane, Fernando
    Högskolan i Borås, Akademin för textil, teknik och ekonomi. KTH-School of Technology and Health.
    Lindecrantz, Kaj
    KTH-School of Technology and Health.
    Haag, Martin
    GECKO Institute, Heilbronn University, Heilbronn, Germany.
    Koch, Sabine
    Department of Learning, Informatics, Management and Ethics, Health Informatics Centre, Karolinska Institute.
    User-Centred Design and Usability Evaluation of a Heart Rate Variability Biofeedback Game2016Ingår i: IEEE Access, E-ISSN 2169-3536, Vol. PP, nr 99, s. 1-1Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background and objective: Reduced heart rate variability (HRV) is an indicatorof a malfunctioning autonomic nervous system. Resonant frequencybreathing is a potential non-invasive means of intervention for improvingthe balance of the autonomic nervous system and increasing HRV. However,such breathing exercises are regarded as boring and monotonous tasks.The use of gaming elements (gamification) or a full gaming experience is awell-recognised method for achieving higher motivation and engagement invarious tasks. However, there is limited documented knowledge on how todesign a game for breathing exercises. In particular, the influence of additionalinteractive elements on the main course of training has not yet beenexplored. In this study, we evaluated the satisfaction levels achieved usingdifferent game elements and how disruptive they were to the main task, i.e.,paced breathing training.

    Methods: An Android flight game was developed with three game modes thatdiffer in the degrees of multitasking they require. Design, development and evaluation were conducted using a user-centred approach, including contextanalysis, the design of game principle mock-ups, the selection of game principlesthrough a survey, the design of the game mechanics and GUI mock-up,icon testing and the performance of a summative study through user questionnairesand interviews. A summative evaluation of the developed gamewas performed with 11 healthy participants (ages 40-67) in a controlled setting.Results: The results confirm the potential of video games for motivatingplayers to engage in HRV biofeedback training. The highest training performanceon the first try was achieved through pure visualisation rather thanin a multitasking mode. Players had higher motivation to play the morechallenging game and were more interested in long-term engagement.Conclusion: A framework for gamified HRV biofeedback research is presented.It has been shown that multitasking has considerable influence onHRV biofeedback and should be used with an adaptive challenge level.

  • 94.
    Zhang, Rui
    et al.
    University of Passau.
    Freund, Martin
    University of Passau.
    Amft, Oliver
    University of Passau.
    Cheng, Jingyuan
    DFKI.
    Zhou, Bo
    DFKI.
    Lukowicz, Paul
    DFKI.
    Seoane, Fernando
    Högskolan i Borås, Akademin för textil, teknik och ekonomi. KTH-School of Technology and Health.
    Chabrecek, Peter
    Sefar AG.
    A Generic Sensor Fabric for Multi-modal Swallowing Sensing in Regular Upper-body Shirts2016Ingår i: Proceedings of the 2016 ACM International Symposium on Wearable Computers, HEIDELBERG: ACM Digital Library , 2016, s. 46-47Konferensbidrag (Refereegranskat)
    Abstract [en]

    We investigate a generic fabric material as basis for resistive pressure and bio-impedance sensors and apply the fabric in a shirt collar for swallowing spotting. A pilot study confirmed the signal performance of both sensor types.

  • 95.
    Zhou, Bo
    et al.
    DFKI.
    Altamirano, Carlos Andres Velez
    DFKI.
    Zurian, Heber Cruz
    DFKI.
    Atefi, Seyed Reza
    Högskolan i Borås, Akademin för textil, teknik och ekonomi.
    Billing, Erik
    Högskolan i Skövde.
    Seoane, Fernando
    Högskolan i Borås, Akademin för textil, teknik och ekonomi. Högskolan i Borås, Akademin för vård, arbetsliv och välfärd. KTH-School of Technology and Health.
    Lukowicz, Paul
    DFKI.
    Textile Pressure Mapping Sensor for Emotional Touch Detection in Human-Robot Interaction2017Ingår i: Sensors, Vol. 17, nr 11Artikel i tidskrift (Refereegranskat)
  • 96.
    Zhou, Bo
    et al.
    DFKI.
    Cruz, Heber Zurian
    DFKI.
    Atefi, Seyed Reza
    Högskolan i Borås, Akademin för textil, teknik och ekonomi. Harvard University.
    Billing, Erik
    Högskolan i Skövde.
    Seoane, Fernando
    Högskolan i Borås, Akademin för textil, teknik och ekonomi. Högskolan i Borås, Akademin för vård, arbetsliv och välfärd. Karolinska Institutet.
    Lukowicz, Paul
    DFKI.
    TouchMe: Full-textile Touch Sensitive Skin for Encouraging Human-Robot Interaction2017Ingår i: The robotic sense of touch: from sensing to understanding, workshop at the IEEE International Conference on Robotics and Automation (ICRA), May 29-June 3, Singapore, 2017Konferensbidrag (Refereegranskat)
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