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  • 1. Löfgren, N.
    et al.
    Lindecrantz, Kaj
    University of Borås, School of Engineering.
    Flisberg, A.
    Bågenholm, R.
    Kjellmer, I.
    Thordstein, M.
    Spectral Distance for ARMA Models Applied to Electroencephalogram for Early Detection of Hypoxia.2006In: Journal of Neural Engineering, ISSN 1741-2560, E-ISSN 1741-2552, Vol. 3, no 3, p. 227-234Article in journal (Refereed)
  • 2.
    Löfhede, Johan
    et al.
    University of Borås, School of Engineering.
    Löfgren, Nils
    Thordstein, Magnus
    Flisberg, Anders
    Kjellmer, Ingemar
    Lindecrantz, Kaj
    University of Borås, School of Engineering.
    Classification of burst and suppression in the neonatal electroencephalogram2008In: Journal of Neural Engineering, ISSN 1741-2560, E-ISSN 1741-2552, Vol. 5, no 4, p. 402-410Article in journal (Refereed)
    Abstract [en]

    Fisher's linear discriminant (FLD), a feed-forward artificial neural network (ANN) and a support vector machine (SVM) were compared with respect to their ability to distinguish bursts from suppressions in electroencephalograms (EEG) displaying a burst-suppression pattern. Five features extracted from the EEG were used as inputs. The study was based on EEG signals from six full-term infants who had suffered from perinatal asphyxia, and the methods have been trained with reference data classified by an experienced electroencephalographer. The results are summarized as the area under the curve (AUC), derived from receiver operating characteristic (ROC) curves for the three methods. Based on this, the SVM performs slightly better than the others. Testing the three methods with combinations of increasing numbers of the five features shows that the SVM handles the increasing amount of information better than the other methods.

  • 3.
    Löfhede, Johan
    et al.
    University of Borås, School of Engineering.
    Thordstein, Magnus
    Löfgren, Nils
    Flisberg, Anders
    Rosa-Zurera, Manuel
    Kjellmer, Ingemar
    Lindecrantz, Kaj
    University of Borås, School of Engineering.
    Automatic classification of background EEG activity in healthy and sick neonates2010In: Journal of Neural Engineering, ISSN 1741-2560, E-ISSN 1741-2552, Vol. 7, no 1Article in journal (Refereed)
    Abstract [en]

    The overall aim of our research is to develop methods for a monitoring system to be used at neonatal intensive care units. When monitoring a baby, a range of different types of background activity needs to be considered. In this work, we have developed a scheme for automatic classification of background EEG activity in newborn babies. EEG from six full-term babies who were displaying a burst suppression pattern while suffering from the after-effects of asphyxia during birth was included along with EEG from 20 full-term healthy newborn babies. The signals from the healthy babies were divided into four behavioural states: active awake, quiet awake, active sleep and quiet sleep. By using a number of features extracted from the EEG together with Fisher’s linear discriminant classifier we have managed to achieve 100% correct classification when separating burst suppression EEG from all four healthy EEG types and 93% true positive classification when separating quiet sleep from the other types. The other three sleep stages could not be classified. When the pathological burst suppression pattern was detected, the analysis was taken one step further and the signal was segmented into burst and suppression, allowing clinically relevant parameters such as suppression length and burst suppression ratio to be calculated. The segmentation of the burst suppression EEG works well, with a probability of error around 4%.

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