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  • 1.
    Balaban, Merve
    et al.
    Department of Molecular Biology and Genetics, Gebze Technical University, Gebze-Kocaeli, 41400 Turkey.
    Koc, Cansel
    Department of Molecular Biology and Genetics, Gebze Technical University, Gebze-Kocaeli, 41400 Turkey.
    Sar, Taner
    University of Borås, Faculty of Textiles, Engineering and Business. Department of Molecular Biology and Genetics, Gebze Technical University, Gebze-Kocaeli, 41400 Turkey.
    Akbas, Meltem Yesilcimen
    Department of Molecular Biology and Genetics, Gebze Technical University, Gebze-Kocaeli, 41400 Turkey.
    Screening for Bioactive Compound Rich Pomegranate Peel Extracts and Their Antimicrobial Activities2022In: Johnson Matthey Technology Review, ISSN 2056-5135, Vol. 66, no 1, p. 81-89Article in journal (Refereed)
    Abstract [en]

    In this work, seven different extracts from pomegranate (Punica granatum L., cv. Hicaznar) peel were prepared by using different solvents (ethanol, methanol, either alone or in combination with acid, acetone and water). The phenolics (punicalagins and ellagic acid), organic acids (citric acid and malic acid) and sugars of pomegranate peel extracts were determined. The highest amounts of punicalagins and ellagic acid were detected by ethanol-acid extract as 13.86% and 17.19% (w/v) respectively, whereas the lowest levels were obtained with acetone and water extracts. Moreover, the methanol-acid (3.19%malic acid) and ethanol-acid (1.13% citric acid) extracts contained the highest levels of organic acids. The antimicrobial activities of extracts were investigated by agar well diffusion method. Methanol-acid and ethanol-acid extracts exhibited the highest antimicrobial effects on all tested microorganisms, giving inhibition zones ranging in size from 17 to 36 mm. Although similar antimicrobial activities were observed by ethanol, methanol, and acetone extracts (up to 24 mm), the lowest antimicrobial activities were attained by water extract (0-15 mm). All extracts were generally more effective against Gram-positive bacteria: Enterococcus facealis, Bacillus subtilis, Bacillus cereus than Gram-negative ones: Escherichia coli and Enterobacter aerogenes. It was shown that extracts from pomegranate peels represent a good source of bioactive compounds.

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