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Association between glycometabolic status in the acute phase and 2½ years after an acute coronary syndrome
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2006 (English)In: Scandinavian Cardiovascular Journal, ISSN 1401-7431, E-ISSN 1651-2006, Vol. 40, no 3, p. 145-151Article in journal (Refereed) Published
Abstract [en]

Objectives. To evaluate the association between glycometabolic status in the acute phase and 2½ years later in patients with acute coronary syndrome (ACS). Methods. Non-diabetic patients (n = 762) presenting with ACS were prospectively followed up for 2½ years. Patients were stratified by admission plasma glucose (<6.1 mmol/l, 6.1 – 6.9 mmol/l and ≥7.0 mmol/l) and HbA1c (≤4.5%, 4.6 – 5.4% and ≥5.5%). The predictive value of glucose levels ≥ 7.0 mmol/l and HbA1c ≥ 5.5% for glycometabolic disturbance (i.e. diabetes or impaired fasting glycaemia (IFG)) was analysed. Results. Of 762 patients, 13% had a diagnosis of diabetes and 16% had IFG at follow-up. The prevalence of glycometabolic disturbance at follow-up increased with increasing plasma glucose at admission, from 19% in patients with < 6.1 mmol/l to 42% in patients with ≥ 7.0 mmol/l. Sixty-one percent of patients with HbA1c ≥ 5.5% had glycometabolic disturbance after 2½ years compared to only 25% of those with HbA1c < 5.5%. Conclusion. Non-diabetic patients with ACS and hyperglycaemia are at high risk for developing glycometabolic disturbance. HbA1c may be an even stronger predictor of glycometabolic disturbance than plasma glucose.

Place, publisher, year, edition, pages
Informa Healthcare , 2006. Vol. 40, no 3, p. 145-151
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Medical and Health Sciences
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URN: urn:nbn:se:hb:diva-8055DOI: 10.1080/14017430600797626Local ID: 2320/9032OAI: oai:DiVA.org:hb-8055DiVA, id: diva2:888938
Available from: 2015-12-22 Created: 2015-12-22 Last updated: 2017-10-09Bibliographically approved

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Herlitz, Johan

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Citation style
  • apa
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More styles
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  • de-DE
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  • nn-NB
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  • Other locale
More languages
Output format
  • html
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  • asciidoc
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