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Post resuscitation care: what are the therapeutic alternatives and what do we know?
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2006 (English)In: Resuscitation, ISSN 0300-9572, E-ISSN 1873-1570, Vol. 69, no 1, 15-22 p.Article in journal (Refereed) Published
Abstract [en]

A large proportion of deaths in the Western World are caused by ischaemic heart disease. Among these patients a majority die outside hospital due to sudden cardiac death. The prognosis among these patients is in general, poor. However, a significant proportion are admitted to a hospital ward alive. The proportion of patients who survive the hospital phase of an out of hospital cardiac arrest varies considerably. Several treatment strategies are applicable during the post resuscitation care phase, but the level of evidence is weak for most of them. Four treatments are recommended for selected patients based on relatively good clinical evidence: therapeutic hypothermia, beta-blockers, coronary artery bypass grafting, and an implantable cardioverter defibrillator. The patient's cerebral function might influence implementation of the latter two alternatives. There is some evidence for revascularisation treatment in patients with suspected myocardial infarction. On pathophysiological grounds, an early coronary angiogram is a reasonable alternative. Further randomised clinical trials of other post resuscitation therapies are essential.

Place, publisher, year, edition, pages
Elsevier Ireland Ltd , 2006. Vol. 69, no 1, 15-22 p.
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Medical and Health Sciences
Identifiers
URN: urn:nbn:se:hb:diva-8039DOI: 10.1016/j.resuscitation.2005.08.006Local ID: 2320/9058OAI: oai:DiVA.org:hb-8039DiVA: diva2:888922
Available from: 2015-12-22 Created: 2015-12-22 Last updated: 2017-09-12Bibliographically approved

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