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Mortality and morbidity during one year of follow-up in suspected acute myocardial infarction in relation to early diagnosis: experiences from the MIAMI trial
[external].
1990 (English)In: Journal of Internal Medicine, ISSN 0954-6820, E-ISSN 1365-2796, Vol. 228, no 2, 125-131 p.Article in journal (Refereed) Published
Abstract [en]

From a large randomized multicentre trial of metoprolol in suspected acute myocardial infarction (n = 5778) we report on the outcome during 1 year of follow-up, in relation to early diagnosis. Patients who developed a confirmed infarction had a 1-year mortality rate of 12.8%. This was significantly higher than the mortality rate of 6.3% (P less than 0.001) in patients with possible infarction and it was also higher than that in patients with no infarction, which was 5.0% (P less than 0.001). A multivariate analysis showed that independent risk predictors in the clinical history of patients without confirmed infarction were a history of angina pectoris, chronic use of digitalis and advanced age. After 1 year, angina pectoris was most common in patients with an initial possible infarction. These patients were also in most urgent need of bypass surgery. We thus conclude that the mortality during 1 year of follow-up among patients with an initially strongly suspected acute myocardial infarction was clearly related to whether or not the patient developed a myocardial infarction.

Place, publisher, year, edition, pages
Wiley-Blackwell Publishing Ltd. , 1990. Vol. 228, no 2, 125-131 p.
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:hb:diva-7667Local ID: 2320/8509OAI: oai:DiVA.org:hb-7667DiVA: diva2:888548
Available from: 2015-12-22 Created: 2015-12-22 Last updated: 2017-09-26Bibliographically approved

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Herlitz, Johan

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