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Metoprolol in acute myocardial infarction. Enzymatic estimation of infarct size. The MIAMI Trial Research Group
[external].
1985 (English)In: American Journal of Cardiology, ISSN 0002-9149, E-ISSN 1879-1913, Vol. 56, no 14, 27-29 p.Article in journal (Refereed) Published
Abstract [en]

The maximum serum activity for aspartate aminotransferase (s-ASAT) during the first 3 days was recorded in 5,507 patients with suspected or definite acute myocardial infarction. The s-ASAT activity was corrected for the normal range from each center. The median s-ASAT activity was 4.9 arbitrary units in the placebo group versus 4.6 arbitrary units in the metoprolol group (p = 0.072). Univariate analyses indicated that the delay time between onset of symptoms and randomization and sympathetic activity at entry significantly influenced the effect of metoprolol. A similar decrease in serum enzyme activity after metoprolol treatment was observed independent of signs of infarct localization on the entry electrocardiogram.

Place, publisher, year, edition, pages
Elsevier Excerpta Medica, Inc. , 1985. Vol. 56, no 14, 27-29 p.
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Medical and Health Sciences
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URN: urn:nbn:se:hb:diva-7612DOI: 10.1016/0002-9149(85)90693-9Local ID: 2320/8485OAI: oai:DiVA.org:hb-7612DiVA: diva2:888492
Available from: 2015-12-22 Created: 2015-12-22 Last updated: 2017-03-21Bibliographically approved

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