With the technological progress of materials science, the palette of colours with which to print on textiles has expanded beyond those with previously known properties and expressions to a new generation, with more advanced functionality and expressive properties. This new range of colours is characterised by their ability when printed on textiles to change colour in relation to external factors and internal programmes; for example, leuco dye-based thermochromic inks generally change colour in response to temperature fluctuations. This research explores the design properties and potentials of leuco dye-based thermochromic inks printed on textiles, with regard to creating a wider range of colour-changing effects for textile applications. The significance of this for textile design is related to the development of a methodology for designing dynamic surface patterns. The research was conducted by creating a series of design experiments using leuco dye-based thermochromic inks, which resulted in different recipes and methods, along with a pedagogical tool. The results highlighted the diverse colour-changing properties of leuco dye-based thermochromic inks, which have the potential to create more complex patterns on textiles. The outcome of this research proposes a foundation for textile designers with which to approach new ways of thinking and designing.