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2021 (English)In: BMJ Open, E-ISSN 2044-6055, Vol. 11, no 4, article id e042340Article in journal (Refereed) Published
Abstract [en]
OBJECTIVE: To compare childbirth experiences in women randomly assigned to either induction of labour at 41 weeks or to expectant management until 42 weeks, in the Swedish Post-term Induction Study.
DESIGN: A register-based, multicentre, randomised, controlled, superiority trial.
SETTING: Women were recruited at 14 hospitals in Sweden, 2016-2018.
PARTICIPANTS: Women with an uncomplicated singleton pregnancy were recruited at 41 gestational weeks.
INTERVENTIONS: The women were randomly assigned to induction of labour at 41 weeks (induction group, n=1381) or expectant management until 42 weeks (expectant management group, n=1379).
OUTCOME MEASURES: As main outcome, women's childbirth experiences were measured using the Childbirth Experience Questionnaire version 2 (CEQ2), in 656 women, 3 months after the birth at three hospitals. As exploratory outcome, overall childbirth experience was measured in 1457 women using a Visual Analogue Scale (VAS 1-10) within 3 days after delivery at the remaining eleven hospitals.
RESULTS: The total response rate was 77% (2113/2760). There were no significant differences in childbirth experience measured with CEQ2 between the groups (induction group, n=354; expectant management group, n=302) in the subscales: own capacity (2.8 vs 2.7, p=0.09), perceived safety (3.3 vs 3.2, p=0.06) and professional support (3.6 vs 3.5, p=0.38) or in the total CEQ2 score (3.3 vs 3.2, p=0.07), respectively. Women in the induction group scored higher in the subscale participation (3.6 vs 3.4, p=0.02), although with a small effect size (0.19). No significant difference was observed in overall childbirth experience according to VAS (8.0 (n=735) vs 8.1 (n=735), p=0.22).
CONCLUSIONS: There were no differences in childbirth experience, according to CEQ2 or overall childbirth experience assessed with VAS, between women randomly assigned to induction of labour at 41 weeks or expectant management until 42 weeks. Overall, women rated their childbirth experiences high.
TRIAL REGISTRATION NUMBER: ISRCTN26113652.
Place, publisher, year, edition, pages
BMJ Publishing Group Ltd, 2021
Keywords
Maternal medicine, obstetrics, reproductive medicine
National Category
Obstetrics, Gynecology and Reproductive Medicine
Identifiers
urn:nbn:se:hb:diva-29565 (URN)10.1136/bmjopen-2020-042340 (DOI)000638218000011 ()33827832 (PubMedID)2-s2.0-85103978394 (Scopus ID)
Note
Funding Agencies:
Swedish government ALFGBG-440301 ALFGBG-718721 ALFGBG-70940 ALFGBG-426401
Health Technology Centre at Sahlgrenska University Hospital
Foundation of the Health and Medical care committee of the region of Västra Götaland, Sweden VGFOUREG387351 VGFOUREG640891 VGFOUREG854081
Hjalmar Svensson Foundation
Foundation Mary von Sydow
Uppsala Örebro Regional Research Council RFR-556711 RFR-736891
Region Örebro County research committee OLL-715501
ALF agreement in Stockholm ALF-561222 ALF-562222 ALF-563222
Centre for Clinical Research Dalarna, Uppsala University, Sweden CKFUU-417011
Born Wijk donation fund
2021-04-142023-03-232023-08-28Bibliographically approved