The increasing emphasis on small series production in higher cost locations is particularly challenging in the textile/apparel industry due to global supply chain configurations. To support (re)configuration in this context, Total interpretive structural modelling (TISM) method is used to gain a deeper understanding of the inter-relationships among configuration/capability related aspects from the literature. TISM interviews were done with 24 industry practitioners producing/sourcing in the EU, or in the process of implementation. The findings validate extensive inter-relations, at the same time highlighting relational aspects, internal integration, and quality as significant drivers. Further in-depth research is required to understand these influences.