A closed loop value chain is a concept that maximises a product’s utility both before and after end-of-life. This chain’s primary components are reuse, repair, up-cycling and down-cycling. This paper reviews the literature in the domain of ‘reuse’ to formulate and propose a conceptual framework for a ‘reuse-based clothing value chain’. We performed a systematic literature review in which a range of online databases were searched to select papers related to reuse between September 1994 and March 2015. Our review is presented broadly and in two parts: the first part provides a descriptive analysis of the articles, and the second part develops propositions based on the textual analysis. The review revealed that there are six primary drivers of the reuse-based clothing value chain: system, redesignability, price, information, legislation, and consumer attitude. Corresponding propositions highlight the key importance of system, product redesignability, product price, information, government legislation and consumer attitude to the economic success of the reuse-based clothing value chain. Finally, this work proposes a conceptual framework based on our propositions. This research may help scholars and practitioners to understand the current state of the literature. The list of references may be considered a source for future research in this area.