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Robustness study of the different immittance spectra and frequency ranges in bioimpedance spectroscopy analysis for assessment of total body composition
Högskolan i Borås, Institutionen Ingenjörshögskolan. (Medical TexTTronics)
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2014 (Engelska)Ingår i: Physiological Measurement, ISSN 0967-3334, E-ISSN 1361-6579, ISSN 0967-3334, Vol. 35, nr 7, s. 1373-Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

The estimation of body fluids is a useful and common practice for assessment of disease status and therapy outcomes. Electrical bioimpedance spectroscopy (EBIS) methods are noninvasive, inexpensive and efficient alternatives for determination of body fluids. One of the main source of errors in EBIS measurements in the estimation of body fluids is capacitive coupling. In this paper an analysis of capacitive coupling in EBIS measurements was performed and the robustness of the different immittance spectra against it tested. On simulations the conductance (G) spectrum presented the smallest overall error, among all immittance spectra, in the estimation of the impedance parameters used to estimate body fluids. Afterwards the frequency range of 10–500 kHz showed to be the most robust band of the G spectrum. The accuracy of body fluid estimations from the resulting parameters that utilized G spectrum and parameters provided by the measuring device were tested on EBIS clinical measurements from growth hormone replacement therapy patients against estimations performed with dilution methods. Regarding extracellular fluid, the correlation between each EBIS method and dilution was 0.93 with limits of agreement of 1.06 ± 2.95 l for the device, 1.10 ± 2.94 l for G [10–500 kHz] and 1.04 ± 2.94 l for G [5–1000 kHz]. Regarding intracellular fluid, the correlation between dilution and the device was 0.91, same as for G [10–500 kHz] and 0.92 for G [5–1000 kHz]. Limits of agreement were 0.12 ± 4.46 l for the device, 0.09 ± 4.45 for G [10–500 kHz] and 0.04 ± 4.58 for G [5–1000 kHz]. Such close results between the EBIS methods validate the proposed approach of using G spectrum for initial Cole characterization and posterior clinical estimation of body fluids status.

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Institute of Physics Publishing Ltd. , 2014. Vol. 35, nr 7, s. 1373-
Nyckelord [en]
Body Composition, Bioimpedance, Biomedical Engineering
Nationell ämneskategori
Annan elektroteknik och elektronik Biofysik
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Integrerad vårdutveckling
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URN: urn:nbn:se:hb:diva-2055DOI: 10.1088/0967-3334/35/7/1373Lokalt ID: 2320/14703OAI: oai:DiVA.org:hb-2055DiVA, id: diva2:870136
Tillgänglig från: 2015-11-13 Skapad: 2015-11-13 Senast uppdaterad: 2017-11-11Bibliografiskt granskad

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Seoane, FernandoLindecrantz, Kaj

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Physiological Measurement
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