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Characteristics, survival and neurological outcome in out-of-hospital cardiac arrest in young adults in Sweden: A nationwide study.
University of Gothenburg, Institute of Medicine, Department of Molecular and Clinical Medicine, Sweden; Sahlgrenska University Hospital, Department of Emergency Medicine, Gothenburg, Sweden.
University of Gothenburg, Institute of Medicine, Department of Molecular and Clinical Medicine, Sweden; Sahlgrenska University Hospital, Department of Cardiology, Gothenburg, Sweden; The Swedish Cardiopulmonary Resuscitation Registry, Centre of Registries, Västra Götaland, Gothenburg, Sweden.
University of Gothenburg, Institute of Medicine, Department of Molecular and Clinical Medicine, Sweden; Sahlgrenska University Hospital, Department of Cardiology, Gothenburg, Sweden.
University of Gothenburg, Institute of Medicine, Department of Molecular and Clinical Medicine, Sweden; Sahlgrenska University Hospital, Department of Cardiology, Gothenburg, Sweden.
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2023 (English)In: Resuscitation Plus, E-ISSN 2666-5204, Vol. 16, article id 100503Article in journal (Refereed) Published
Abstract [en]

AIM: The aim of this study was to present a comprehensive overview of out-of-hospital cardiac arrests (OHCA) in young adults.

METHODS: The data set analyzed included all cases of OHCA from 1990 to 2020 in the age-range 16-49 years in the Swedish Registry of Cardiopulmonary Resuscitation (SRCR). OHCA between 2010 and 2020 were analyzed in more detail. Clinical characteristics, survival, neurological outcomes, and long-time trends in survival were studied. Logistic regression was used to study 30-days survival, neurological outcomes and Utstein determinants of survival.

RESULTS: Trends were assessed in 11,180 cases. The annual increase in 30-days survival during 1990-2020 was 5.9% with no decline in neurological function among survivors. Odds ratio (OR) for heart disease as the cause was 0.55 (95% CI 0.44 to 0.67) in 2017-2020 compared to 1990-1993. Corresponding ORs for overdoses and suicide attempts were 1.61 (95% CI 1.23-2.13) and 2.06 (95% CI 1.48-2.94), respectively. Exercise related OHCA was noted in roughly 5%. OR for bystander CPR in 2017-2020 vs 1990-1993 was 3.11 (95% CI 2.57 to 3.78); in 2020 88 % received bystander CPR. EMS response time increased from 6 to 10 minutes.

CONCLUSION: Survival has increased 6% annually, resulting in a three-fold increase over 30 years, with stable neurological outcome. EMS response time increased with 66% but the majority now receive bystander CPR. Cardiac arrest due to overdoses and suicide attempts are increasing.

Place, publisher, year, edition, pages
2023. Vol. 16, article id 100503
Keywords [en]
Cardiac arrest, Cardiovascular disease, OHCA, Survival
National Category
Cardiac and Cardiovascular Systems
Research subject
The Human Perspective in Care
Identifiers
URN: urn:nbn:se:hb:diva-31220DOI: 10.1016/j.resplu.2023.100503PubMedID: 38026135OAI: oai:DiVA.org:hb-31220DiVA, id: diva2:1826236
Available from: 2024-01-11 Created: 2024-01-11 Last updated: 2024-01-19Bibliographically approved

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